Role of Peptides in Skeletal Muscle Wasting: A Scoping Review
This scoping review highlights the potential of peptides as biomarkers and intervention targets for muscle wasting. It connects the cellular receptors and signaling pathways linking peptides with skeletal muscle wasting. Improving clinical translation requires addressing study design limitations, incorporating more representative study populations and adhering to standardized reporting guidelines. The application of machine learning can support the identification of novel bioactive peptides.
Authors
- Anton De Spiegeleer (ORCID: https://orcid.org/0000-0002-3681-2807)
- Evelien Wynendaele (ORCID: https://orcid.org/0000-0003-0969-7580)
- Katarzyna Goljanek‐Whysall (ORCID: https://orcid.org/0000-0001-8166-8800)
- Ewerton Cristhian Lima de Oliveira (ORCID: https://orcid.org/0000-0002-2338-7178)
- Christophe Van de Wiele (ORCID: https://orcid.org/0000-0002-4370-5954)
- Vincent Mouly (ORCID: https://orcid.org/0000-0003-3809-4033)
- Kauê Santana da Costa (ORCID: https://orcid.org/0000-0002-2735-8016)
- Petar Naumovski
- Bart De Spiegeleer
- Aster Wakjira
Institutions
- Universidade Federal do Oeste do Pará (BR)
- Jimma University (ET)
- Inserm (FR)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Ghent University Hospital (BE)
- Ghent University (BE)
- Sorbonne Université (FR)
- Institut de Myologie (FR)
- COPE Galway (IE)
- Vale Technological Institute (BR)
- Centre de Recherche en Myologie
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1002/jcsm.70109
- Citations
- 2
- Primary Topic
- Protein Hydrolysis and Bioactive Peptides
- Type
- article
- Field-Weighted Citation Impact
- 1.61