Changes of in-vivo markers of platelet activation during the menstrual cycle in healthy pre-menopausal female individuals
In healthy pre-menopausal female subjects, changes of in-vivo platelet activation markers are associated with changes of PG and gonadotropins. These findings suggest the need for caution in the interpretation of platelet biomarkers in clinical studies enrolling pre-menopausal female individuals.
Authors
- Marzia Miglionico (ORCID: https://orcid.org/0000-0001-6937-0075)
- Annamaria Sabetta (ORCID: https://orcid.org/0000-0002-0516-6662)
- Sebastiano Sciarretta (ORCID: https://orcid.org/0000-0002-8633-6896)
- Stefania Basili (ORCID: https://orcid.org/0000-0002-6987-1926)
- Lucia Stefanini (ORCID: https://orcid.org/0000-0001-7420-301X)
- Tania D’Amico (ORCID: https://orcid.org/0000-0001-5303-0164)
- Laura Napoleone
- Andrea Lenzi (ORCID: https://orcid.org/0000-0002-7711-0465)
- Alessandra D’Amico (ORCID: https://orcid.org/0000-0002-5571-4583)
- Roberto Carnevale (ORCID: https://orcid.org/0000-0002-6216-9595)
- Giulio Francesco Romiti (ORCID: https://orcid.org/0000-0002-3788-8942)
- Valeria Raparelli (ORCID: https://orcid.org/0000-0002-2100-5682)
- Cristina Nocella (ORCID: https://orcid.org/0000-0003-4398-6327)
- Giacomo Frati (ORCID: https://orcid.org/0000-0003-2703-3761)
- Francesca Maiorca (ORCID: https://orcid.org/0000-0002-5412-5760)
- Roberto Cangemi (ORCID: https://orcid.org/0000-0002-4097-2061)
- Lombardi Ludovica
Institutions
- University of Liverpool (GB)
- Istituto Neurologico Mediterraneo (IT)
- Liverpool Heart and Chest Hospital (GB)
- European University of Rome (IT)
- Università degli Studi Internazionali di Roma (IT)
- Istituto Pasteur (IT)
- Liverpool John Moores University (GB)
- Universitat de Barcelona (ES)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1038/s43856-025-01240-8
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission