Comparison of the additive value of blood-based and retinal biomarkers to clinical features in predicting cognitive decline
A multimodal model comprising blood, retinal and clinical variables may represent an accessible, non-invasive tool for predicting cognitive decline.
Authors
- Narayanaswamy Venketasubramanian (ORCID: https://orcid.org/0000-0003-3593-6362)
- Leopold Schmetterer (ORCID: https://orcid.org/0000-0002-7189-1707)
- Christopher Chen (ORCID: https://orcid.org/0000-0002-1047-9225)
- Mark Richards (ORCID: https://orcid.org/0000-0002-2023-8177)
- Victor Yuan (ORCID: https://orcid.org/0000-0002-3394-998X)
- Eugene S.J. Tan (ORCID: https://orcid.org/0000-0001-7273-6883)
- Oi Wah Liew (ORCID: https://orcid.org/0000-0001-5729-2700)
- Joyce Ruifen Chong (ORCID: https://orcid.org/0000-0002-2869-0096)
- Saima Hilal (ORCID: https://orcid.org/0000-0001-5434-5635)
- Lieng Hsi Ling (ORCID: https://orcid.org/0000-0001-6063-8530)
- Yuek Ling Chai (ORCID: https://orcid.org/0000-0001-6646-1553)
- Ming Ann Sim (ORCID: https://orcid.org/0000-0002-5699-3553)
- Hyungwon Choi (ORCID: https://orcid.org/0000-0002-6687-3088)
- Mitchell K.P. Lai (ORCID: https://orcid.org/0000-0001-7685-1424)
- Yih Chung Tham (ORCID: https://orcid.org/0000-0002-6752-797X)
- Jessica Yan Xia Ng
- Liuyun Wu
- Siew Pang Chan
- Jacqueline Chua
- Boon Yeow Tan
- Jenny Pek Ching Chong (ORCID: https://orcid.org/0000-0002-4182-188X)
Institutions
- National University of Singapore (SG)
- Chinese University of Hong Kong (HK)
- Singapore National Eye Center (SG)
- Raffles Institution (SG)
- Ng Teng Fong General Hospital (SG)
- National University Heart Centre Singapore (SG)
- Duke-NUS Medical School (SG)
- National University Hospital (SG)
- National University Health System (SG)
- St Luke's Hospital (SG)
- University of Otago (NZ)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1038/s43856-025-01237-3
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National University of Singapore
- National University Health System
- Medical Research Council
- National Medical Research Council