Neuroanatomical dimensions in major depression linked to cognition, adverse life events, self-harm, metabolomics and genetics

D1 and D2 represent distinct neurobiological mechanisms underlying MDD. The validation in a general population-based cohort and in a cohort sample with depressive symptoms delineates mechanisms underlying heterogeneity in MDD.

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Publication Details

Journal
Communications Medicine
Published
2025-11-15
DOI
https://doi.org/10.1038/s43856-025-01219-5
Citations
1
Primary Topic
Neurotransmitter Receptor Influence on Behavior
Type
article
Field-Weighted Citation Impact
0.91

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article

Neuroanatomical dimensions in major depression linked to cognition, adverse life events, self-harm, metabolomics and genetics

Beata R. Godlewska, Ashish Singh, Irina A. Strigo, Yuhan Cui et al.
1 citations
Communications Medicine
Neurotransmitter Receptor Influence on Behavior
0.91
article

Neuroanatomical dimensions in major depression linked to cognition, adverse life events, self-harm, metabolomics and genetics

Beata R. Godlewska, Ashish Singh, Irina A. Strigo, Yuhan Cui, Andrew Mark McIntosh, Duygu Tosun, Wenyi Xiao, Stephen C. Strother, Chao‐Gan Yan, J.F.W. Deakin, Rachel D. Woodham, Dongtao Wei, Catherine J. Harmer, Gitte M. Knudsen, Cynthia H.Y. Fu, Mathilde Antoniades, Helen S. Mayberg, Susan Rotzinger, Stephen R. Arnott, Güray Erus, Vibe G. Frøkjær, Melanie Ganz, Yong Fan, Jonathan Savitz, Christos A. Davatzikos, Sidney H. Kennedy, Aleks Stolicyn, Ian H. Gotlib, Boadie W. Dunlop, Haochang Shou, Allan H. Young, Benicio Noronha Frey, Qiyong Gong, Cherise Chin-Fatt, Stefanie Hassel, Kun Qin, Ki Sueng Choi, Ian Anderson, W. Edward Craighead, Madhukar H. Trivedi, Martin P. Paulus, Junhao Wen, Heather C. Whalley, José García, Dhivya Srinivasan, Matthew D. Sacchet, Jiang Qiu, Keith Ho
article en
1 citations

Abstract

D1 and D2 represent distinct neurobiological mechanisms underlying MDD. The validation in a general population-based cohort and in a cohort sample with depressive symptoms delineates mechanisms underlying heterogeneity in MDD.

Communications MedicineVol. 5(1)
University of Copenhagen (DK), Hubei University of Medicine (CN), University Health Network (CA), Harvard University (US), Southwest University (CN), Emory University (US), University of East London (GB), University of Calgary (CA), University of California, San Francisco (US), King's College London (GB), University of Toronto (CA), Xiamen University (CN), South London and Maudsley NHS Foundation Trust (GB), Sichuan University (CN), Oxford Health NHS Foundation Trust (GB), Baycrest Hospital (CA), Edinburgh Cancer Research (GB), Rigshospitalet (DK), Edinburgh Royal Infirmary (GB), Warneford Hospital (GB), University of California System (US), University of Manchester (GB), University of Oxford (GB), Massachusetts General Hospital (US), West China Hospital of Sichuan University (CN), Circuit Therapeutics (United States) (US), Taihe Hospital (CN), Penn Center for AIDS Research (US), Centre for Global Health Research (CA), Capital Region of Denmark (DK), Laureate Institute for Brain Research (US), St. Joseph’s Healthcare Hamilton (CA), University of Pennsylvania (US), The University of Texas Southwestern Medical Center (US), Stanford University (US), McMaster University (CA), Icahn School of Medicine at Mount Sinai (US), Tsinghua University (CN)
National Alliance for Research on Schizophrenia and Depression, Wellcome Trust, LivaNova, Michael Smith Health Research BC, National Institute for Health and Care Research, H. Lundbeck A/S, Victoria General Hospital Foundation, Canadian Institutes of Health Research, Medical Research Council, National Institute of Mental Health
Openalex Percentile: Top 20%
Neurotransmitter Receptor Influence on Behavior
0.91
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