The Impact of Radiation Dose to Bowel on the Risk of Developing Gastrointestinal Toxicities When Treating Abdominopelvic Soft-Tissue Sarcomas With Preoperative Radiation Therapy
Traditional RT volumetric bowel dose constraints are frequently exceeded, given the large size of AP-STS at presentation and the corresponding large RT volumes. Exceeding the conventional bowel dosimetric constraints should not dissuade the use of RT, but instead signal the need for aggressive prophylactic management of potential toxicities.
Authors
- Wang Xa
- Caroline Scally
- Lim Ty
- Devarati Mitra (ORCID: https://orcid.org/0000-0002-2225-164X)
- Ahsan Saleem Farooqi (ORCID: https://orcid.org/0000-0001-9605-7113)
- Alison K. Yoder (ORCID: https://orcid.org/0000-0002-2606-3814)
- Callistus Nguyen (ORCID: https://orcid.org/0000-0003-4832-869X)
- Haitao Wang (ORCID: https://orcid.org/0000-0001-6910-974X)
- Dan Luo (ORCID: https://orcid.org/0000-0001-6074-1298)
- Bishop AJ
- C Wang
- Thrower SL
- Roland CL
- Lyu H
- Netherton TJ
- Guadagnolo BA
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1016/j.adro.2025.101953
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- University of Texas MD Anderson Cancer Center
- National Cancer Institute