Immune Responses to SARS-CoV-2 Variants WT and XBB.1.9: Assessing Vulnerabilities and Preparedness
These findings demonstrate substantially reduced neutralization of XBB.1.9 compared to WT and reveal disparities in WT immunity by age and region. The results emphasize the need for updated vaccines targeting immune-evasive variants and for tailored vaccination strategies to address regional and demographic gaps in protection.
Authors
- Enosh Tomer
- Menucha Jurkowicz (ORCID: https://orcid.org/0009-0008-7167-384X)
- Lital Keinan-Boker
- Limor Kliker
- Yaniv Lustig (ORCID: https://orcid.org/0000-0001-7949-5912)
- Neta S. Zuckerman (ORCID: https://orcid.org/0000-0001-6074-2100)
- Ravit Bassal (ORCID: https://orcid.org/0000-0002-0086-2968)
- Victoria Indenbaum (ORCID: https://orcid.org/0000-0002-7675-0591)
- Michal Mandelboim (ORCID: https://orcid.org/0000-0002-5997-7241)
Institutions
- Tel Aviv University (IL)
- Israel Ministry of Health (IL)
- University of Haifa (IL)
Publication Details
- Journal
- Vaccines
- Published
- 2025-11-16
- DOI
- https://doi.org/10.3390/vaccines13111167
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tel Aviv University