A Unique Metastatic Spread of Lung Adenocarcinoma to The Stomach: A Case Report and Literature Review.

Lung cancer is a leading cause of cancer-related deaths and commonly spreads to the brain, bones, liver, and adrenal glands. Gastric metastases from lung cancer are uncommon and can occur in melanoma, breast cancer, and lung cancer. Most patients show no symptoms at presentation; however, metastasis from lung cancer portends a poor prognosis. This case report highlights a rare instance of lung cancer metastasizing to the stomach in a 60-year-old female that was detected incidentally on a PET scan. The scan showed two new stomach masses with increased FDG uptake and contrast enhancement. The patient had chemoimmunotherapy after receiving palliative radiotherapy to the stomach for gastric metastasis. Clinicians should maintain a high index of suspicion while monitoring gastrointestinal symptoms in patients with a history of lung cancer. Gastric metastases can sometimes mimic primary gastric malignancies on imaging/endoscopy, which can impact initial workup and delay correct diagnosis.

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Publication Details

Journal
Journal of Community Hospital Internal Medicine Perspectives
Published
2025-11-14
DOI
https://doi.org/10.55729/2000-9666.1547
Primary Topic
Metastasis and carcinoma case studies
Type
article
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article

A Unique Metastatic Spread of Lung Adenocarcinoma to The Stomach: A Case Report and Literature Review.

Hafiz Muhammad Aslam, Ammad Naeem, Aniqa Faraz
Journal of Community Hospital Internal Medicine Perspectives
Metastasis and carcinoma case studies
article

A Unique Metastatic Spread of Lung Adenocarcinoma to The Stomach: A Case Report and Literature Review.

Hafiz Muhammad Aslam, Ammad Naeem, Aniqa Faraz
article en

Abstract

Lung cancer is a leading cause of cancer-related deaths and commonly spreads to the brain, bones, liver, and adrenal glands. Gastric metastases from lung cancer are uncommon and can occur in melanoma, breast cancer, and lung cancer. Most patients show no symptoms at presentation; however, metastasis from lung cancer portends a poor prognosis. This case report highlights a rare instance of lung cancer metastasizing to the stomach in a 60-year-old female that was detected incidentally on a PET scan. The scan showed two new stomach masses with increased FDG uptake and contrast enhancement. The patient had chemoimmunotherapy after receiving palliative radiotherapy to the stomach for gastric metastasis. Clinicians should maintain a high index of suspicion while monitoring gastrointestinal symptoms in patients with a history of lung cancer. Gastric metastases can sometimes mimic primary gastric malignancies on imaging/endoscopy, which can impact initial workup and delay correct diagnosis.

Journal of Community Hospital Internal Medicine PerspectivesVol. 15(6)
Charleston Area Medical Center (US), Beacon Health System (US), Cumberland Medical Center (US), Elkhart Clinic (US)
Openalex Percentile: Top 50%
Metastasis and carcinoma case studies
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A Unique Metastatic Spread of Lung Adenocarcinoma to The Stomach: A Case Report and Literature Review. — Hafiz Muhammad Aslam, Ammad Naeem, et al. · Journal of Community Hospital Internal Medicine Perspectives (2025) | TGRS Research Map | TGRS