Public Knowledge and Attitude Toward Down Syndrome: A Nationwide Cross-sectional Survey in Jordan

Abstract Introduction: Down syndrome (DS) is a widespread chromosomal abnormality affecting 1 in 1000 births, associated with intellectual disabilities, physical impairments, and social stigma. The present study aims to assess the Jordanian population’s knowledge about and attitudes toward the condition. Methodology: A cross-sectional study was conducted through a survey questionnaire distributed among the general population of Jordan between September 2023 and November 2023. Results: A total of 806 participants responded to this survey, with 63.03% females and a mean age of 29 ± 11.68, the majority (74.07%) had a university education and 57.57% had medical backgrounds, approximately 98.64% were aware of DS previously. Respondents displayed a predominantly positive attitude, with 78.16% expressing willingness to befriend individuals with DS. Conclusion: The adequate knowledge of Jordanian people toward DS correlates with generally positive attitudes. Females, young individuals, and those with high-income level showed a higher knowledge and more favorable attitude toward people with DS. Our results could direct educational efforts among specific demographic groups to enhance understanding and promote inclusivity of people with DS.