Ameliorative effects of combination therapy with metformin and crocin in experimental colitis in rats
MTF, crocin, and their combined administration exerted ameliorative effects in the colons of acetic acid-induced colitis rats, which is probably due to their anti-inflammatory and antioxidant properties. Further experimental studies are required to elucidate the underlying mechanisms.
Authors
- Mohsen Minaiyan
- Mohammad Hashemnia (ORCID: https://orcid.org/0000-0002-2899-4794)
- Mohammad Hossein Aarabi (ORCID: https://orcid.org/0000-0001-6514-4492)
- Bahare Koohshekan
Institutions
- Isfahan University of Medical Sciences (IR)
- Razi University (IR)
Publication Details
- Journal
- Research in Pharmaceutical Sciences
- Published
- 2025-11-01
- DOI
- https://doi.org/10.4103/rps.rps_121_24
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00