Intravascular Large B-Cell Lymphoma Presenting as Migraine with Aura: A Case Report

The initial presentation of migraine with aura was not previously described. Nonspecific initial laboratory studies, preexisting Waldenstrom's macroglobulinemia which explained splenomegaly, absence of masses in the chest, abdomen, and pelvis, absence of lymphadenopathy, and MRI imaging mimicking multiple sclerosis made the diagnostic process exceedingly difficult. We demonstrate another presentation of this rare and fatal disease and hope that the reader will consider this differential diagnostic possibility when evaluating patients with rapidly worsening neurological symptoms.