Lipoprotein(a) and long-term structural valve degeneration of aortic bioprostheses

Elevated Lp(a) is independently associated with long-term risk of stenotic/mixed SVD. These findings highlight Lp(a) as a promising biomarker of prosthetic valve vulnerability and support investigation of emerging Lp(a)-lowering therapies to improve valve durability.

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Publication Details

Journal
European Heart Journal - Cardiovascular Imaging
Published
2025-11-16
DOI
https://doi.org/10.1093/ehjci/jeaf320
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
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article

Lipoprotein(a) and long-term structural valve degeneration of aortic bioprostheses

Joëlle Kefer, Anne–Catherine Pouleur, Agnès Pasquet, David Vancraeynest et al.
European Heart Journal - Cardiovascular Imaging
Lipoproteins and Cardiovascular Health
article

Lipoprotein(a) and long-term structural valve degeneration of aortic bioprostheses

Joëlle Kefer, Anne–Catherine Pouleur, Agnès Pasquet, David Vancraeynest, Bernhard Gerber, Didier Gruson, Christophe Beauloye, David De Azevedo, Sandrine Horman, Laurent de Kerchove, Frédéric Maes, Sophie Piérard, Marin Boute, Paul Salembier
article en

Abstract

Elevated Lp(a) is independently associated with long-term risk of stenotic/mixed SVD. These findings highlight Lp(a) as a promising biomarker of prosthetic valve vulnerability and support investigation of emerging Lp(a)-lowering therapies to improve valve durability.

European Heart Journal - Cardiovascular ImagingVol. 27(2)
Cliniques Universitaires Saint-Luc (BE), UCLouvain (BE)
Openalex Percentile: Top 47%
Lipoproteins and Cardiovascular Health
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