SIRT3-activating, biodegradable poly-honokiol with high drug loading for thoracic aortic dissection therapy
Collectively, these findings demonstrate that poly-honokiol is a potent preventive candidate for TAD, offering both high drug-loading efficiency and targeted mitochondrial protection.
Authors
- Siyu Han (ORCID: https://orcid.org/0000-0001-8709-5564)
- Gang Tan (ORCID: https://orcid.org/0000-0001-8096-4798)
- Xinan Qiao (ORCID: https://orcid.org/0009-0001-6365-9086)
- Lingjie Meng
- Longteng Wang (ORCID: https://orcid.org/0000-0002-0904-8081)
- He Sun (ORCID: https://orcid.org/0000-0002-5315-3014)
- Weixun Duan (ORCID: https://orcid.org/0000-0003-4475-7067)
- Liqing Jiang (ORCID: https://orcid.org/0000-0002-2595-9109)
- Daquan Wang (ORCID: https://orcid.org/0000-0002-2215-7776)
- Bin Zhang (ORCID: https://orcid.org/0000-0001-8835-8370)
- Jiali Wang (ORCID: https://orcid.org/0000-0002-3640-5910)
- Liyun Zhang (ORCID: https://orcid.org/0000-0002-0814-4872)
- Hanzhao Zhu
- Xiangyan Peng
Institutions
- Xijing Hospital (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jare.2025.11.028
- Primary Topic
- Magnolia and Illicium research
- Type
- article
- Field-Weighted Citation Impact
- 0.00