Impact of processing and analysis methodology on thalamic susceptibility assessment in multiple sclerosis
Our study suggests high reproducibility of group-level clinical studies using QSM to study the thalamus in pwMS. In particular, methodological differences in processing and analysis are unlikely to explain contradicting findings of thalamic susceptibility in MS.
Authors
- Jack A. Reeves (ORCID: https://orcid.org/0009-0002-4079-5664)
- Ferdinand Schweser (ORCID: https://orcid.org/0000-0003-0399-9211)
- Michael G. Dwyer (ORCID: https://orcid.org/0000-0003-4684-4658)
- Dejan Jakimovski (ORCID: https://orcid.org/0000-0001-7114-4958)
- Niels Bergsland (ORCID: https://orcid.org/0000-0002-7792-0433)
- Bianca Weinstock‐Guttman (ORCID: https://orcid.org/0000-0001-6732-151X)
- Fahad Salman (ORCID: https://orcid.org/0009-0000-3873-2301)
- Robert Zivadinov (ORCID: https://orcid.org/0000-0002-7799-1485)
- Abhisri Ramesh
Institutions
- Strong Memorial Hospital (US)
- Jacobs Institute (US)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1371/journal.pone.0332478
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Sanofi
- Emory University
- EMD Serono