Integrating multiparametric MRI radiomics and clinical models to assess sensitivity to neoadjuvant chemotherapy in breast cancer: A multicenter study
The SHAP-explainable radiomic-clinical model provides a clinically applicable, noninvasive tool for pretreatment stratification of NAC sensitivity. This approach enhances personalized therapeutic decision-making while minimizing unnecessary treatment toxicity.
Authors
- Xinyi Zeng (ORCID: https://orcid.org/0009-0002-1771-8310)
- Jidong Peng (ORCID: https://orcid.org/0000-0003-0014-9211)
- Xiaofei Tang (ORCID: https://orcid.org/0000-0001-6557-7722)
- Jinxin Chen (ORCID: https://orcid.org/0000-0002-0729-5214)
- Xianjun Zeng
Institutions
- Nanchang University (CN)
- Ganzhou People's Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/acm2.70347
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00