Assessment of <i>Leishmania</i> exposure in blood donors from a non‐endemic urban area: A study in São Paulo
The absence of Leishmania DNA in ELISA-reactive samples highlights the limitations of serological screening in low-endemicity areas. Inflammatory physiological conditions, such as pregnancy and abortion, may contribute to non-specific reactivity. The incorporation of molecular methods and the adoption of universal leukoreduction are recommended measures to ensure transfusion safety and avoid unnecessary donor deferrals.
Authors
- Vanderson Rocha (ORCID: https://orcid.org/0000-0003-0094-619X)
- José Ângelo Lauletta Lindoso (ORCID: https://orcid.org/0000-0002-4971-7876)
- Nanci A. Salles (ORCID: https://orcid.org/0000-0001-7580-4597)
- Norival Kesper (ORCID: https://orcid.org/0000-0003-4076-0461)
- Alfredo Mendrone (ORCID: https://orcid.org/0000-0002-3090-4575)
- Kátia Cristina Dantas (ORCID: https://orcid.org/0000-0003-1346-9003)
- Anna S. Nishiya (ORCID: https://orcid.org/0000-0002-0623-1999)
- Juliana Derriga
- Cláudia Maria de Castro Gomes (ORCID: https://orcid.org/0000-0001-9909-9466)
- Suzete C. Ferreira (ORCID: https://orcid.org/0000-0002-4190-0238)
- Cesar de Almeida‐Neto (ORCID: https://orcid.org/0000-0002-8490-4634)
- I. Lima (ORCID: https://orcid.org/0009-0007-6361-0139)
- Jerenice Esdras Ferreira
- Silvia Petrossi Gallo Polato
- Tila Fanciani
Institutions
- Universidade de São Paulo (BR)
- Instituto Adolfo Lutz (BR)
- Instituto de Medicina Tropical (PY)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Vox Sanguinis
- Published
- 2025-11-16
- DOI
- https://doi.org/10.1111/vox.70146
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Universidade de São Paulo