Probiotics in Women's Health: Mechanisms, Benefits, and Potential Applications for Preventing Bacterial Vaginosis and Sexually Transmitted Diseases in Sexual Health Products

This review summarizes key clinical findings on probiotics in addressing bacterial vaginosis (BV) and sexually transmitted diseases (STDs) in women. Lactobacillus bacteria play a critical role in maintaining a balanced vaginal microbiome by supporting an acidic environment and helping combat conditions like BV, AIDS, maternal group B Streptococcus (GBS), and candidiasis. Probiotics, either alone or combined with antibiotics, have shown promise in promoting microbiome recovery and potentially reducing recovery time. However, their efficacy depends on the strains used and specific conditions, emphasizing the need for further research. Additionally, probiotics can mitigate risks associated with excessive antibiotic use, including antibiotic resistance. The increasing interest in probiotics for women's sexual health has led to the development of specialized products, though identifying superior strains and optimal dosages remains an ongoing challenge. In conclusion, probiotics offer a non-invasive and cost-effective approach to supporting women's health by promoting microbiota balance and enhancing immune function. They offer a promising strategy for managing BV and potentially reducing STD risks. However, further research is necessary to standardize strains, dosages, and application methods in order to achieve consistent and effective outcomes.

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Publication Details

Journal
Apmis
Published
2025-11-01
DOI
https://doi.org/10.1111/apm.70086
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
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article

Probiotics in Women's Health: Mechanisms, Benefits, and Potential Applications for Preventing Bacterial Vaginosis and Sexually Transmitted Diseases in Sexual Health Products

Sajjad Babaei, Anahita Barghi, Mahsa Sadeghi, Babak Haghshenas et al.
Apmis
Reproductive tract infections research
article

Probiotics in Women's Health: Mechanisms, Benefits, and Potential Applications for Preventing Bacterial Vaginosis and Sexually Transmitted Diseases in Sexual Health Products

Sajjad Babaei, Anahita Barghi, Mahsa Sadeghi, Babak Haghshenas, Yousef Nami, Tara Farhadi
article en

Abstract

This review summarizes key clinical findings on probiotics in addressing bacterial vaginosis (BV) and sexually transmitted diseases (STDs) in women. Lactobacillus bacteria play a critical role in maintaining a balanced vaginal microbiome by supporting an acidic environment and helping combat conditions like BV, AIDS, maternal group B Streptococcus (GBS), and candidiasis. Probiotics, either alone or combined with antibiotics, have shown promise in promoting microbiome recovery and potentially reducing recovery time. However, their efficacy depends on the strains used and specific conditions, emphasizing the need for further research. Additionally, probiotics can mitigate risks associated with excessive antibiotic use, including antibiotic resistance. The increasing interest in probiotics for women's sexual health has led to the development of specialized products, though identifying superior strains and optimal dosages remains an ongoing challenge. In conclusion, probiotics offer a non-invasive and cost-effective approach to supporting women's health by promoting microbiota balance and enhancing immune function. They offer a promising strategy for managing BV and potentially reducing STD risks. However, further research is necessary to standardize strains, dosages, and application methods in order to achieve consistent and effective outcomes.

ApmisVol. 133(11)
Kermanshah University of Medical Sciences (IR), Agricultural Biotechnology Research Institute of Iran (IR), Dong-A University (KR)
Openalex Percentile: Top 67%
Reproductive tract infections research
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