Mesenchymal Stromal Cells Mitigate Prolonged Cardiopulmonary Bypass-Induced Neuroinflammation
BM-MSC administration via CPB shows promise for reducing extensive inflammatory stress. Further investigation using this model will elucidate CPB-induced unique pathological events in the developing brain and mechanisms underlying the therapeutic actions of BM-MSC.
Authors
- Kamil Sarkışlalı
- Nemanja Sarić (ORCID: https://orcid.org/0000-0001-5336-4180)
- David Zurakowski (ORCID: https://orcid.org/0000-0003-3610-6942)
- Kei Kobayashi (ORCID: https://orcid.org/0000-0002-8815-9029)
- Nobuyuki Ishibashi (ORCID: https://orcid.org/0000-0002-7910-4050)
- Takuya Maeda (ORCID: https://orcid.org/0000-0003-0912-4643)
- Akihisa Furuta (ORCID: https://orcid.org/0000-0001-9223-9067)
- Patrick J. Hanley (ORCID: https://orcid.org/0000-0002-0102-7892)
- Chase D. McCann (ORCID: https://orcid.org/0000-0002-9178-2110)
Institutions
- Boston University (US)
- Boston Children's Hospital (US)
- Children's National (US)
- Harvard University (US)
- George Washington University (US)
- Center for Cancer and Blood Disorders (US)
Publication Details
- Journal
- Interdisciplinary CardioVascular and Thoracic Surgery
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1093/icvts/ivaf267
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00