A systematic review and meta-analysis of liver xenotransplantation from genetically modified pigs to nonhuman primates
The results indicate that pig-to-NHP liver xenotransplantation has limited short-term survival, with coagulopathy being a major challenge. Further research is needed to optimize this procedure and facilitate its clinical translation.
Authors
- Jie Xiang (ORCID: https://orcid.org/0000-0001-8937-3564)
- Xinyu Yu (ORCID: https://orcid.org/0000-0002-3689-980X)
- Pingbo Jin (ORCID: https://orcid.org/0000-0002-5540-7014)
- Ying Chen (ORCID: https://orcid.org/0000-0002-7769-216X)
- Wei Zhang (ORCID: https://orcid.org/0009-0007-8335-8663)
- Rongrong Wang (ORCID: https://orcid.org/0000-0003-0615-0838)
- Xueli Bai
- Xiazhen Yu (ORCID: https://orcid.org/0000-0002-6656-4664)
- Tingbo Liang (ORCID: https://orcid.org/0000-0003-0143-3353)
- Guoliang Qiao
Institutions
- Ministry of Public Health (MG)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1097/js9.0000000000003929
- Primary Topic
- Xenotransplantation and immune response
- Type
- article
- Field-Weighted Citation Impact
- 0.00