Causal mediation of immune cells in autoimmune liver diseases and oral cancer risk: a Mendelian randomization study
This study provides the first genetic evidence establishing PSC as a causal risk factor for OCC via immune cell mediation, offering translational potential for enhanced surveillance, early detection protocols, and targeted immunotherapies in high-risk AILD patients.
Authors
- Qiong Gao (ORCID: https://orcid.org/0000-0002-0406-1594)
- Jukun Song (ORCID: https://orcid.org/0000-0003-2542-9340)
- Xudong Tian (ORCID: https://orcid.org/0000-0002-7584-6102)
- WU Ya (ORCID: https://orcid.org/0000-0003-1686-9715)
- Zhenglong Tang
- Weili Wang (ORCID: https://orcid.org/0000-0002-9145-5603)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1097/js9.0000000000004072
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00