CHMP4C promotes the malignant progression of bladder cancer by regulating the PI3K/AKT pathway

The high expression of CHMP4C may be associated with poor prognosis, tumor grading, and sensitivity to immunotherapy in bladder cancer. By promoting cell proliferation, migration, and invasion, while inhibiting apoptosis and advancing the cell cycle, CHMP4C facilitates the progression of bladder cancer. CHMP4C influences the development of bladder cancer by activating the PI3K/Akt pathway.

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Publication Details

Journal
International Journal of Surgery
Published
2025-11-13
DOI
https://doi.org/10.1097/js9.0000000000003726
Primary Topic
Ubiquitin and proteasome pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

CHMP4C promotes the malignant progression of bladder cancer by regulating the PI3K/AKT pathway

Weiqing Song, Zong-liang Zhang, Xiaorui Chen, Xueying Tan et al.
International Journal of Surgery
Ubiquitin and proteasome pathways
article

CHMP4C promotes the malignant progression of bladder cancer by regulating the PI3K/AKT pathway

Weiqing Song, Zong-liang Zhang, Xiaorui Chen, Xueying Tan, Jiangshui Yuan
article en

Abstract

The high expression of CHMP4C may be associated with poor prognosis, tumor grading, and sensitivity to immunotherapy in bladder cancer. By promoting cell proliferation, migration, and invasion, while inhibiting apoptosis and advancing the cell cycle, CHMP4C facilitates the progression of bladder cancer. CHMP4C influences the development of bladder cancer by activating the PI3K/Akt pathway.

International Journal of SurgeryVol. 112(2)
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN), Qingdao Municipal Hospital (CN)
Openalex Percentile: Top 69%
Ubiquitin and proteasome pathways
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