Synchronized aging trajectory of facial and skeletal morphology in Chinese females: implications for rejuvenation strategies

Skeletal and facial aging are interrelated but occur asynchronously, with skeletal aging preceding soft tissue changes. The rapid acceleration of facial aging at approximately 35 years highlights the need for early intervention, with a focus on preserving skeletal structure before 40 years of age to maintain facial harmony. Skeletal rejuvenation and soft tissue restoration should be considered in tandem, particularly in the midface and jawline regions, for effective and long-lasting rejuvenation outcomes. This study underscores the clinical importance of early, anatomy-informed interventions tailored to age-related changes to enhance clinical decision-making and optimize personalized rejuvenation strategies.