Optimization of Chemical Defined Medium for <i>Lactobacillus brevis</i> Based on Artificial Intelligence
Determine the requirements of <i>Lactobacillus brevis</i> growth for various types of amino acids, vitamins, and nucleotides.A combination of artificial intelligence algorithms and Growth Profiler 960 (GP960) equipment is used to optimize the medium at high throughput.No restrictions are placed on the factors and levels of medium optimization.Compared to complex medium, the components of the synthetic medium for <i>Lactobacillus brevis</i> are clearer and less expensive.
Authors
- Yu Chang (ORCID: https://orcid.org/0000-0003-2348-8806)
- Jianye Xia (ORCID: https://orcid.org/0000-0003-2114-5770)
- Xu Yang (ORCID: https://orcid.org/0000-0002-2006-9406)
- Xiaoqing Ren
Institutions
- Tianjin Agricultural University (CN)
- Tianjin University of Science and Technology (CN)
- Tianjin Institute of Industrial Biotechnology (CN)
Publication Details
- Journal
- Engineering in Life Sciences
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/elsc.70051
- Primary Topic
- Machine Learning in Bioinformatics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China