Targeting peptide homes to spinal cord injury in a rat model
CAQK rapidly and selectively localizes to injured spinal cord tissue in a dose-responsive manner, with peak accumulation observed within 24 hours. These findings support its potential as a targeted delivery vector for injectable therapeutics in acute SCI.
Authors
- Rachel M. Russo (ORCID: https://orcid.org/0000-0002-5971-5508)
- Eric C. Reynolds (ORCID: https://orcid.org/0000-0002-6618-4856)
- José A. García del Castillo (ORCID: https://orcid.org/0000-0003-3646-1477)
- M.-Y Lee
- Christopher D. Pivetti (ORCID: https://orcid.org/0000-0002-1362-2058)
- Maryam-sadat Shahin
- Michael Le
- Kuan‐Wei Huang (ORCID: https://orcid.org/0000-0002-1937-645X)
- Gabriel Urreola (ORCID: https://orcid.org/0009-0006-4363-2843)
- Aijun Wang (ORCID: https://orcid.org/0000-0002-2985-3627)
- Timothy Tran (ORCID: https://orcid.org/0000-0003-1606-0860)
- Kaitlin Clark
- A. Ratcliff
- Sina Vatoofy
- Jay Uppuluri
- Emma Loll
- Andrei M.T. Dangan
- Solomon Bannerman
Institutions
- MACOM (United States) (US)
Publication Details
- Journal
- The Journal of Trauma: Injury, Infection, and Critical Care
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1097/ta.0000000000004819
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00