A prospective observational study of inflammatory mediators in cerebrospinal fluid after intraoperative radiotherapy of brain tumors
IORT induces distinct changes in levels of IM, which may contribute to improved tumor control. These findings provide novel insights into the immunomodulatory effects of IORT and may have implications for optimizing multimodal treatment strategies for malignant brain tumors. As an exploratory study with a limited sample size, the findings should be interpreted as hypothesis-generating.
Authors
- Bruno Märkl (ORCID: https://orcid.org/0000-0002-7704-850X)
- Ina Konietzko
- Ehab Shiban
- Klaus-Henning Kahl (ORCID: https://orcid.org/0000-0002-0545-1367)
- Tina Schaller (ORCID: https://orcid.org/0000-0003-2295-8810)
- Philipp Krauß (ORCID: https://orcid.org/0000-0002-0127-1000)
- Friederike Liesche‐Starnecker (ORCID: https://orcid.org/0000-0003-1948-1580)
- Nicola Jungbäck (ORCID: https://orcid.org/0000-0002-8483-5720)
- Dorothée Mielke (ORCID: https://orcid.org/0000-0002-1462-4864)
- Tatiana Mögele
- Zuzanna Mielewczyk
Institutions
- University of Augsburg (DE)
- University Hospital Augsburg (DE)
- Medizinische Universität Lausitz - Carl Thiem (DE)
Publication Details
- Journal
- Therapeutic Advances in Medical Oncology
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1177/17588359251389740
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00