Combined ε-Toxin Nanovaccine with Enhanced Immunity for Effective Protection in a Murine Model
These findings demonstrate that MNP-ASP-ETX can be considered a novel vaccine for the prevention of ETX intoxication and provide new strategies for designing and developing toxin vaccines.
Authors
- Lin Kang (ORCID: https://orcid.org/0000-0002-9186-9574)
- Shan Gao (ORCID: https://orcid.org/0000-0002-5962-290X)
- Xinyu Fang (ORCID: https://orcid.org/0000-0002-3503-7765)
- Wenwen Xin (ORCID: https://orcid.org/0000-0001-5468-2084)
- Bing Yuan (ORCID: https://orcid.org/0009-0007-9062-0383)
- Jiaxin Li (ORCID: https://orcid.org/0000-0003-2674-5388)
- Jing Wang (ORCID: https://orcid.org/0000-0001-5901-0797)
- Tingting Liu (ORCID: https://orcid.org/0000-0001-9623-7114)
- Xi Luo (ORCID: https://orcid.org/0000-0002-4793-0315)
- Dongxue Li (ORCID: https://orcid.org/0000-0001-5302-8347)
- Baohua Zhao (ORCID: https://orcid.org/0009-0004-0323-5283)
- Li Tang (ORCID: https://orcid.org/0000-0002-3415-9402)
- Yanwei Li (ORCID: https://orcid.org/0009-0008-3939-6360)
- Jinglin Wang (ORCID: https://orcid.org/0009-0007-7503-2401)
Institutions
- Academy of Military Medical Sciences (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
- Hebei Normal University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/ijn.s530074
- Primary Topic
- Toxin Mechanisms and Immunotoxins
- Type
- article
- Field-Weighted Citation Impact
- 0.00