SeraSeq reference materials support non-invasive cfDNA screening methods
Seraseq reference materials closely mimic the cfDNA characteristics of maternal plasma and perform reliably across multiple testing dimensions. While they may present slight differences in fragment size periodicity, these did not affect analytical performance. These materials are therefore suitable for validating and monitoring NIPT workflows.
Authors
- Sylvie Giroux (ORCID: https://orcid.org/0000-0001-7515-5267)
- André Caron (ORCID: https://orcid.org/0000-0003-3648-1179)
- François Rousseau (ORCID: https://orcid.org/0000-0002-4504-5507)
- Seyedeh Saideh Daryabari (ORCID: https://orcid.org/0000-0003-1951-0847)
Institutions
- Hôtel-Dieu de Québec (CA)
- Hôpital Saint-François d'Assise (CA)
- Centre hospitalier de l'Université Laval (CA)
- Université Laval (CA)
Publication Details
- Journal
- Clinical Biochemistry
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1016/j.clinbiochem.2025.111046
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00