Liriopesides B inhibits proliferation and metastasis and induces apoptosis of oral squamous cell carcinoma via the PI3K/Akt/mTOR signaling pathway
LPB exerts anti-OSCC properties by modulating the PI3K/Akt/mTOR cascade with minimal biological toxicity, highlighting its potential as a therapeutic agent for OSCC.
Authors
- Xuanping Huang (ORCID: https://orcid.org/0000-0002-1023-1019)
- Binghua Feng
- Xiaoping Su (ORCID: https://orcid.org/0000-0003-1824-943X)
- Jinzhi Wei
- Cuiping Li (ORCID: https://orcid.org/0000-0002-9483-6452)
- Hejia Guo
- Wei Lv (ORCID: https://orcid.org/0009-0004-0820-8620)
Institutions
- Guangxi Medical University (CN)
- Guangxi Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tcr-2025-613
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00