Understanding the bidirectional relationship between chronic respiratory disease and cardiovascular disease using genetic evidence
While we found limited genetic evidence linking CRD and CVD, smoking and inflammatory markers commonly affect both. These findings highlight the complexity of CRD-CVD comorbidities, whose pathophysiology likely does not involve direct causation of each other.
Authors
- Verena Zuber (ORCID: https://orcid.org/0000-0001-9827-1877)
- Jennifer Kathleen Quint (ORCID: https://orcid.org/0000-0003-0149-4869)
- Naesilla Naesilla (ORCID: https://orcid.org/0000-0003-2038-6345)
Institutions
- UK Dementia Research Institute (GB)
- MRC Centre for Environment and Health
- Imperial College London (GB)
Publication Details
- Journal
- Thorax
- Published
- 2025-11-15
- DOI
- https://doi.org/10.1136/thorax-2024-222908
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- UK Research and Innovation
- Alzheimer's Society
- UK Dementia Research Institute
- Medical Research Council