Probable scrub typhus-like infection in Colombia: seroconversion and serological reactivity to Orientia spp. among patients with acute undifferentiated febrile illness in Villeta municipality
This study provides serological evidence of Orientia circulation among febrile patients in Villeta, Colombia, including clear cases of seroconversion. Western blot validated reactivity against immunodominant proteins. Findings suggest a local scrub typhus-like illness and highlight the need for pathogen isolation and genetic characterization to clarify its contribution to AUFI.
Authors
- Nicole L. Mendell (ORCID: https://orcid.org/0009-0007-2551-7769)
- Patricia A. Crocquet-Valdes (ORCID: https://orcid.org/0000-0002-2079-0076)
- Peter C. Melby (ORCID: https://orcid.org/0000-0001-7320-7406)
- David H. Walker (ORCID: https://orcid.org/0000-0002-3309-4360)
- Miguel M. Cabada (ORCID: https://orcid.org/0000-0003-2545-6197)
- Marylin Hidalgo (ORCID: https://orcid.org/0000-0001-8960-0616)
- Patricia V. Aguilar
- Carlos Ramiro Silva-Ramos
Institutions
- Pontificia Universidad Javeriana (CO)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- Travel Medicine and Infectious Disease
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.tmaid.2025.102937
- Citations
- 1
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.05