Single-cell analysis of tumor microenvironment immune homeostasis and identification of prognostic biomarkers in head and neck squamous cell carcinoma

This study provides valuable insights into the immune dynamics of HNSCC and identifies a prognostic risk model based on key immune-related genes, aiding in personalized treatment strategies. The findings offer a novel approach for precise prognostic evaluation and targeted therapy development in HNSCC, advancing clinical management and patient outcomes.

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Publication Details

Journal
Translational Cancer Research
Published
2025-10-01
DOI
https://doi.org/10.21037/tcr-2025-999
Citations
2
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
1.61
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article

Single-cell analysis of tumor microenvironment immune homeostasis and identification of prognostic biomarkers in head and neck squamous cell carcinoma

Shenling Liao, Hongyu Xie, Ga Liao, Libo Liang
2 citations
Translational Cancer Research
Single-cell and spatial transcriptomics
1.61
article

Single-cell analysis of tumor microenvironment immune homeostasis and identification of prognostic biomarkers in head and neck squamous cell carcinoma

Shenling Liao, Hongyu Xie, Ga Liao, Libo Liang
article en
2 citations

Abstract

This study provides valuable insights into the immune dynamics of HNSCC and identifies a prognostic risk model based on key immune-related genes, aiding in personalized treatment strategies. The findings offer a novel approach for precise prognostic evaluation and targeted therapy development in HNSCC, advancing clinical management and patient outcomes.

Translational Cancer ResearchVol. 14(10)
Sichuan University (CN), West China Medical Center of Sichuan University (CN), West China Hospital of Sichuan University (CN), Stomatology Hospital (CN), State Key Laboratory of Oral Diseases
Openalex Percentile: Top 14%
Single-cell and spatial transcriptomics
1.61
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