The influence of depression onset timing after gastrointestinal diseases on dementia risk
Dementia risk was highest when depression began within 6 months of GI disease diagnosis. Findings support gut-brain axis kinks in psychiatric and cognitive comorbidity. Dementia risk varied by timing of depression after GI disease diagnosis. Early treatment of depression in GI patients may lower future dementia risk.
Authors
- Jun Pyo Kim (ORCID: https://orcid.org/0000-0003-4376-3107)
- Seung Hyun Baek (ORCID: https://orcid.org/0000-0002-2778-0938)
- Dong‐Gyu Jo (ORCID: https://orcid.org/0000-0003-2271-1076)
- Suji Hong (ORCID: https://orcid.org/0009-0002-7712-6624)
- Sang Won Seo (ORCID: https://orcid.org/0000-0002-8747-0122)
Institutions
- Samsung Medical Center (KR)
- Suwon Research Institute (KR)
- Advanced Institute of Convergence Technology (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/alz.70899
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Korea Technology and Information Promotion Agency for SMEs