Applying Precision Medicine to the Heterogeneity of Asthma Attacks
Asthma attacks are complex episodes with diverse causes, endotypes, and phenotypes. Emerging evidence supports incorporating biomarkers (blood eosinophils, Feno, and microbial testing) into clinical assessment to refine management. Recent evidence expands our understanding of exacerbation mechanisms, highlighting the need for tailored management strategies. Recognizing asthma heterogeneity could shift care toward precision medicine, reducing OCS reliance and improving patient outcomes.
Authors
- C.A. Celis-Preciado (ORCID: https://orcid.org/0000-0001-8405-4513)
- Sanjay Ramakrishnan (ORCID: https://orcid.org/0000-0002-3003-7918)
- Imran Howell (ORCID: https://orcid.org/0000-0002-6033-0488)
- Praveen Akuthota (ORCID: https://orcid.org/0000-0001-6655-7520)
- Michael Wechsler
- Simon Couillard (ORCID: https://orcid.org/0000-0002-4057-6886)
- Elsa Ben Hamou Kuijpers
Institutions
- Université de Sherbrooke (CA)
- The University of Western Australia (AU)
- Nuffield Orthopaedic Centre (GB)
- University of California System (US)
- National Jewish Health (US)
- University of California San Diego (US)
- University of Oxford (GB)
- Institute for Respiratory Health (AU)
- Hospital Universitario San Ignacio (CO)
- University of Colorado Denver (US)
Publication Details
- Journal
- CHEST Journal
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.chest.2025.11.013
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00