Locus Coeruleus <scp>MR</scp> Measured Signal Intensity in Fibromyalgia Relative to Healthy Controls
This study is the first report using MR measured signal intensity of the LC to examine noradrenergic function in participants with fibromyalgia. There was no difference in signal intensity when comparing patients to controls, nor did it associate with any symptoms or associated features of fibromyalgia. This suggests that lifetime noradrenergic function may not distinguish fibromyalgia.
Authors
- Cheryl R. McCreary (ORCID: https://orcid.org/0000-0003-1572-010X)
- Marilena M. DeMayo (ORCID: https://orcid.org/0000-0002-9722-6027)
- Alexander McGirr (ORCID: https://orcid.org/0000-0002-8425-3958)
- Clifford Cassidy (ORCID: https://orcid.org/0000-0002-9683-440X)
- Tuan Trang (ORCID: https://orcid.org/0000-0003-3309-9492)
- Ashley Harris (ORCID: https://orcid.org/0000-0003-0414-5832)
Institutions
- University of Calgary (CA)
- Alberta Children's Hospital (CA)
- Hotchkiss Brain Institute (CA)
- Stony Brook University (US)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/ejp.70173
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00