Virulence and Genomic Profiles of Klebsiella pneumoniae Isolated from Pediatric Patients in Henan, China (2021–2023)
The ST11-KL47-KPC2 genotype was the predominant CRKP isolate in pediatric patients. The close genomic relatedness between pediatric and adult CRKP isolates suggests a common ancestor that has disseminated across populations. The high prevalence and clonal transmission of pediatric iuc<sup>+</sup>rmpA2<sup>+</sup> CRKP strains warrant heightened clinical vigilance.
Authors
- Mei Zeng (ORCID: https://orcid.org/0000-0002-3491-5298)
- Yibing Cheng (ORCID: https://orcid.org/0000-0003-3932-6334)
- Junzhen Zhu (ORCID: https://orcid.org/0000-0002-1519-8764)
- Kaijie Gao
- Baoliang Wang (ORCID: https://orcid.org/0000-0002-0045-0576)
- Junwen Yang (ORCID: https://orcid.org/0000-0002-4740-1181)
- Chu-ning Wang
- He Tian
- Yue Qiu (ORCID: https://orcid.org/0000-0002-9132-710X)
Institutions
- Zhengzhou Children's Hospital (CN)
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Current Medical Science
- Published
- 2025-11-17
- DOI
- https://doi.org/10.1007/s11596-025-00137-w
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fudan University