Automated measurement of macular neovascularization lesion size in nAMD using AI segmentation

AI-based segmentation of HRM on OCT scans demonstrates strong overall agreement with manual MNV measurements, particularly on longitudinal assessments. Despite some AI-based overestimations occurring at baseline and some manual MNV underestimations during follow-up, measurements between both methods were highly comparable over time.

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Publication Details

Journal
Graefe s Archive for Clinical and Experimental Ophthalmology
Published
2025-11-17
DOI
https://doi.org/10.1007/s00417-025-07007-0
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
0.00

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OCT
article

Automated measurement of macular neovascularization lesion size in nAMD using AI segmentation

J. Wolf, Daniel Pauleikhoff, Jens Schröter, Laurenz Pauleikhoff et al.
Graefe s Archive for Clinical and Experimental Ophthalmology
Retinal Imaging and Analysis
article

Automated measurement of macular neovascularization lesion size in nAMD using AI segmentation

J. Wolf, Daniel Pauleikhoff, Jens Schröter, Laurenz Pauleikhoff, Lukas Heine, Anna Vahldiek, Benja Vahldiek, Michael Swora, Lars Reissberg
article en

Abstract

AI-based segmentation of HRM on OCT scans demonstrates strong overall agreement with manual MNV measurements, particularly on longitudinal assessments. Despite some AI-based overestimations occurring at baseline and some manual MNV underestimations during follow-up, measurements between both methods were highly comparable over time.

Graefe s Archive for Clinical and Experimental OphthalmologyVol. 264(2)
RWI – Leibniz Institute for Economic Research (DE), Universität Hamburg (DE), University of Münster (DE), University Medical Center Hamburg-Eppendorf (DE), Essen University Hospital (DE), West German Heart and Vascular Center Essen (DE)
Universität Duisburg-Essen
Openalex Percentile: Top 51%
Retinal Imaging and Analysis
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