The burden of tuberculosis and drug resistance in 22 Sub-Saharan African countries, 1990–2021: a GBD 2021 analysis and progress towards WHO 2035 targets with projections to 2050
Despite overall declines in TB mortality, the growing DR-TB/MDR-TB/XDR-TB epidemic, significant subregional disparities, and systemic health system challenges threaten progress toward WHO End TB goals. Strengthening diagnostics, expanding treatment access, integrating care services, and addressing key metabolic and behavioral risk factors are essential to accelerate TB control efforts and align SSA with the 2035 targets.
Authors
- Shu Zhou (ORCID: https://orcid.org/0000-0002-9138-477X)
- Yusheng Cheng (ORCID: https://orcid.org/0000-0003-0044-005X)
- Liqin Zhang (ORCID: https://orcid.org/0000-0002-3632-4117)
- Lei Zha (ORCID: https://orcid.org/0000-0003-4897-0703)
- Emmanuel Mensah (ORCID: https://orcid.org/0000-0002-4644-8674)
- Shuoshuo Wei
- Wei Lu (ORCID: https://orcid.org/0000-0001-6520-9647)
- Min Liu (ORCID: https://orcid.org/0000-0002-5059-3743)
- Shirong Li (ORCID: https://orcid.org/0009-0008-3509-8585)
- Lingling Pan (ORCID: https://orcid.org/0000-0001-6491-2760)
- Hui Zhao (ORCID: https://orcid.org/0000-0003-1327-2577)
Institutions
- Wannan Medical College (CN)
- Bengbu Medical College (CN)
- Anhui Medical University (CN)
- Wuhu Fourth People Hospital (CN)
- Takoradi Technical University (GH)
- Second Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
- Anhui Normal University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1695592
- Citations
- 2
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Wannan Medical College