Cutaneous granular cell tumor presenting as a solitary preauricular nodule: a case report

A 32-year-old female patient visited our hospital due to a solitary firm nodule in the right preauricular area for 4 years. Histopathological manifestations of the skin were nested tumor tissue in the dermis, with polygonal tumor cells, which had abundant cytoplasm filled with eosinophilic granules, and were stained pale pink. Immunohistochemical markers like S-100, vimentin and CD68 were positive. She was diagnosed with cutaneous granular cell tumor and treated by complete resection.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-11-17
DOI
https://doi.org/10.3389/fmed.2025.1689453
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Cutaneous granular cell tumor presenting as a solitary preauricular nodule: a case report

Xiaomei Han, Jialu Song, Yi Cheng, Lu Zhao et al.
Frontiers in Medicine
Tumors and Oncological Cases
article

Cutaneous granular cell tumor presenting as a solitary preauricular nodule: a case report

Xiaomei Han, Jialu Song, Yi Cheng, Lu Zhao, Caixia Hu
article en

Abstract

A 32-year-old female patient visited our hospital due to a solitary firm nodule in the right preauricular area for 4 years. Histopathological manifestations of the skin were nested tumor tissue in the dermis, with polygonal tumor cells, which had abundant cytoplasm filled with eosinophilic granules, and were stained pale pink. Immunohistochemical markers like S-100, vimentin and CD68 were positive. She was diagnosed with cutaneous granular cell tumor and treated by complete resection.

Frontiers in MedicineVol. 12
Hebei Medical University (CN), Fourth Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 52%
Tumors and Oncological Cases
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