Angiogenesis-osteogenesis coupling lithium-loaded bioglass/GelMA hydrogel for bone regeneration
This study presented a novel multi-functional regenerative strategy that simultaneously targeted osteogenesis, angiogenesis, and adipogenesis, using lithium-integrated bioactive hydrogel, offering a comprehensive and promising therapeutic platform beyond conventional bone grafts.
Authors
- Zerui Wu
- Gaoran Ge (ORCID: https://orcid.org/0000-0002-5535-7483)
- Ye Gu (ORCID: https://orcid.org/0000-0003-1751-908X)
- Shuo Feng (ORCID: https://orcid.org/0000-0002-1739-6385)
- Zhihang Xiao
- Dechun Geng (ORCID: https://orcid.org/0000-0003-4375-2803)
- Guo‐Chun Zha (ORCID: https://orcid.org/0000-0001-5423-2083)
- Qiaoqiao Ma
- Heng Xie (ORCID: https://orcid.org/0009-0002-6421-8554)
- Kai Chen (ORCID: https://orcid.org/0000-0002-8647-1182)
- Xiaobin Guo (ORCID: https://orcid.org/0000-0001-5256-9301)
- Peixin Liu (ORCID: https://orcid.org/0000-0002-9417-5025)
- Shujun Lv
- Bingzhen Zhan
Institutions
- Jiangsu University (CN)
- Xinjiang Medical University (CN)
- Xuzhou Medical College (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Soochow University (CN)
- Haikou City People's Hospital (CN)
- Xuzhou Cancer Hospital (CN)
- Changshu No.1 People's Hospital (CN)
- Xuzhou No.1 People's Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
- Beijing Fengtai Hospital (CN)
- The Fifth People’s Hospital of Suzhou (CN)
Publication Details
- Journal
- Biomaterials Advances
- Published
- 2025-11-17
- DOI
- https://doi.org/10.1016/j.bioadv.2025.214591
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00