First implementation of photon-counting detector computed tomography for optimizing segmentation in head-and-neck cancer radiotherapy
The study established the feasibility of PCD-CT for radiotherapy planning. PCD-CT-based delineation provides results comparable to EID-CT, with the added advantages of reduced radiation dose, improved image quality and higher delineation confidence. Significant improvements in delineating specific structures, such as the lips and oral cavity, were observed when combining multiple energy levels in PCD-CT.
Authors
- Matthias Gückenberger (ORCID: https://orcid.org/0000-0002-7146-9071)
- Patrick Wohlfahrt (ORCID: https://orcid.org/0000-0002-2121-0934)
- Niccolò Bertini (ORCID: https://orcid.org/0009-0006-1053-6265)
- Panagiotis Balermpas (ORCID: https://orcid.org/0000-0001-5261-6446)
- L. Wilke (ORCID: https://orcid.org/0000-0002-0702-2355)
- S. Psoroulas (ORCID: https://orcid.org/0000-0001-7576-3238)
- Hatem Alkadhi (ORCID: https://orcid.org/0000-0002-2581-2166)
- Laura Motisi
- Hubert S. Gabryś (ORCID: https://orcid.org/0000-0001-5657-8432)
- Eugenia Vlaskou
- Stephanie Tanadini-Lang
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Siemens Healthineers (Germany) (DE)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.phro.2025.100864
- Citations
- 1
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.88