Global disproportionality analysis of anxiolytic medication-associated cardiovascular and motor impairment disorders, 1967–2024: An international pharmacovigilance database
Although our findings did not allow for causal inference, anxiolytics are effective in managing anxiety disorder symptoms, but safety concerns persist, especially related to cardiovascular and motor dysfunctions.
Authors
- Jaeyu Park (ORCID: https://orcid.org/0009-0005-2009-386X)
- Suein Choi (ORCID: https://orcid.org/0000-0001-5438-7819)
- Hyesu Jo (ORCID: https://orcid.org/0009-0004-1895-300X)
- Kyeongmin Lee (ORCID: https://orcid.org/0009-0004-0379-2151)
- Selin Woo (ORCID: https://orcid.org/0000-0001-7961-2074)
- Dong Keon Yon (ORCID: https://orcid.org/0000-0003-1628-9948)
- Laurent Boyer (ORCID: https://orcid.org/0000-0002-2608-6696)
- Jaehyeong Cho (ORCID: https://orcid.org/0000-0001-7213-5033)
- Tae Hyeon Kim (ORCID: https://orcid.org/0000-0002-9723-2136)
- Xuerong Wen (ORCID: https://orcid.org/0000-0002-4803-7895)
- Sheng‐Min Wang (ORCID: https://orcid.org/0000-0002-1707-9435)
- Guillaume Fond
- Jiyeon Oh (ORCID: https://orcid.org/0009-0005-3291-4370)
Institutions
- University of Rhode Island (US)
- Aix-Marseille Université (FR)
- Assistance Publique Hôpitaux de Marseille (FR)
- St. Mary's Hospital (US)
- Kyung Hee University Medical Center (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1016/j.jad.2025.120629
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00