Sex differences in plaque burden and outcomes in symptomatic patients with suspected coronary artery disease

This study demonstrates important sex-based differences in CAD phenotype and prognosis. Women had lower plaque burden, yet experienced adverse events with lower CAD-RADS, suggesting that current risk stratification may underestimate their risk. AI-QCT provides enhanced plaque characterization, which may in the future improve individualized assessment, especially in women.

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Publication Details

Journal
International Journal of Cardiology
Published
2025-11-12
DOI
https://doi.org/10.1016/j.ijcard.2025.134023
Citations
1
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
Field-Weighted Citation Impact
1.36
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article

Sex differences in plaque burden and outcomes in symptomatic patients with suspected coronary artery disease

Teemu Maaniitty, Antti Saraste, Dávid Molnár, Juhani Knuuti et al.
1 citations
International Journal of Cardiology
Cardiac Imaging and Diagnostics
1.36
article

Sex differences in plaque burden and outcomes in symptomatic patients with suspected coronary artery disease

Teemu Maaniitty, Antti Saraste, Dávid Molnár, Juhani Knuuti, J. J. Bax
article en
1 citations

Abstract

This study demonstrates important sex-based differences in CAD phenotype and prognosis. Women had lower plaque burden, yet experienced adverse events with lower CAD-RADS, suggesting that current risk stratification may underestimate their risk. AI-QCT provides enhanced plaque characterization, which may in the future improve individualized assessment, especially in women.

International Journal of CardiologyVol. 444
Leiden University Medical Center (NL)
Openalex Percentile: Top 14%
Cardiac Imaging and Diagnostics
1.36
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