Multifocal tenosynovial giant cell tumor: A case report

Tenosynovial giant cell tumor is a rare, generally benign soft tissue lesion arising from the synovial lining of joints, bursae, or tendon sheaths. It most commonly presents as a solitary, localized mass in the small joints of the hands and feet. Diagnosis can be difficult due to clinical overlap with other soft tissue masses. Imaging and histopathologic confirmation are critical for diagnosis, while management decisions are guided by considerations of tumor extent, symptom burden, and patient preference, with close follow-up to monitor progression. Surgical excision remains the standard treatment; however, observation may be appropriate in select cases with minimal functional impairment. This case illustrates a rare presentation in a 56-year-old male with multifocal involvement of noncontiguous digits and highlights the importance of clinical awareness of unusual presentations and supporting individualized treatment planning.

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Publication Details

Journal
Radiology Case Reports
Published
2025-11-16
DOI
https://doi.org/10.1016/j.radcr.2025.10.050
Primary Topic
Musculoskeletal synovial abnormalities and treatments
Type
article
Field-Weighted Citation Impact
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article

Multifocal tenosynovial giant cell tumor: A case report

Majid Chalian, Sara Haseli, Mohammed M Kanani
Radiology Case Reports
Musculoskeletal synovial abnormalities and treatments
article

Multifocal tenosynovial giant cell tumor: A case report

Majid Chalian, Sara Haseli, Mohammed M Kanani
article en

Abstract

Tenosynovial giant cell tumor is a rare, generally benign soft tissue lesion arising from the synovial lining of joints, bursae, or tendon sheaths. It most commonly presents as a solitary, localized mass in the small joints of the hands and feet. Diagnosis can be difficult due to clinical overlap with other soft tissue masses. Imaging and histopathologic confirmation are critical for diagnosis, while management decisions are guided by considerations of tumor extent, symptom burden, and patient preference, with close follow-up to monitor progression. Surgical excision remains the standard treatment; however, observation may be appropriate in select cases with minimal functional impairment. This case illustrates a rare presentation in a 56-year-old male with multifocal involvement of noncontiguous digits and highlights the importance of clinical awareness of unusual presentations and supporting individualized treatment planning.

Radiology Case ReportsVol. 21(2)
University of Washington Medical Center (US)
Openalex Percentile: Top 51%
Musculoskeletal synovial abnormalities and treatments
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