Insight differences between deficit and non-deficit schizophrenia: a systematic review and meta-analysis

DS patients exhibit significantly poorer insight than NDS, which was linked to primary enduring negative symptoms and cognitive dysfunction, particularly metacognitive impairments in self-reflection. Rehabilitative interventions targeting these dysfunctions may improve insight and outcomes. Limitations of this study were heterogeneity of insight instruments, few meta-analysable datasets, and low-certainty evidence according to the GRADE assessment.

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Publication Details

Journal
Journal of Psychiatric Research
Published
2025-11-16
DOI
https://doi.org/10.1016/j.jpsychires.2025.11.012
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Insight differences between deficit and non-deficit schizophrenia: a systematic review and meta-analysis

Javier-David López-Moríñigo, Rosa Ayesa‐Arriola, Álvaro López‐Díaz, Claudia Parás et al.
Journal of Psychiatric Research
Schizophrenia research and treatment
article

Insight differences between deficit and non-deficit schizophrenia: a systematic review and meta-analysis

Javier-David López-Moríñigo, Rosa Ayesa‐Arriola, Álvaro López‐Díaz, Claudia Parás, Lucía Colmenero-Capote
article en

Abstract

DS patients exhibit significantly poorer insight than NDS, which was linked to primary enduring negative symptoms and cognitive dysfunction, particularly metacognitive impairments in self-reflection. Rehabilitative interventions targeting these dysfunctions may improve insight and outcomes. Limitations of this study were heterogeneity of insight instruments, few meta-analysable datasets, and low-certainty evidence according to the GRADE assessment.

Journal of Psychiatric ResearchVol. 193
Marqués de Valdecilla University Hospital (ES), Instituto de Investigación Marqués de Valdecilla (ES), Instituto de Biomedicina de Sevilla (ES), Medical Research Network (US), Universidad de Sevilla (ES)
Openalex Percentile: Top 59%
Schizophrenia research and treatment
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