Antidiabetic agents and male fertility: unraveling the impact of glucose-lowering therapies on sperm quality in diabetic males—a narrative review

Current evidence supports the potential of certain antihyperglycemic agents in mitigating diabetes-related male infertility, though drug-specific and context-dependent effects must be considered. Further phenotype-targeted studies are needed to optimize clinical treatment strategies.

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Publication Details

Journal
Translational Andrology and Urology
Published
2025-10-01
DOI
https://doi.org/10.21037/tau-2025-440
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00
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article

Antidiabetic agents and male fertility: unraveling the impact of glucose-lowering therapies on sperm quality in diabetic males—a narrative review

Jian‐Ping Luo, Li Shi, Zisheng Luo, Wang Li et al.
Translational Andrology and Urology
Sperm and Testicular Function
article

Antidiabetic agents and male fertility: unraveling the impact of glucose-lowering therapies on sperm quality in diabetic males—a narrative review

Jian‐Ping Luo, Li Shi, Zisheng Luo, Wang Li, Lina Wang, Guangmei Xie
article en

Abstract

Current evidence supports the potential of certain antihyperglycemic agents in mitigating diabetes-related male infertility, though drug-specific and context-dependent effects must be considered. Further phenotype-targeted studies are needed to optimize clinical treatment strategies.

Translational Andrology and UrologyVol. 14(10)
Gansu Provincial Maternal and Child Health Hospital (CN)
Openalex Percentile: Top 56%
Sperm and Testicular Function
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Antidiabetic agents and male fertility: unraveling the impact of glucose-lowering therapies on sperm quality in diabetic males—a narrative review — Jian‐Ping Luo, Li Shi, et al. · Translational Andrology and Urology (2025) | TGRS Research Map | TGRS