Understanding Clubfoot: Integrating Historical Origins, Embryologic Foundations, Epidemiology and Etiology—A Review

CTEV should be considered a systemic developmental dysplasia rather than an isolated foot deformity. The persistence of recurrence and long-term morbidity underscores the need for multidisciplinary research integrating genetics, developmental biology, biomechanics and rehabilitation. Improved understanding of the etiological mechanisms may enable earlier detection, targeted interventions and ultimately better long-term outcomes for affected individuals.

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Publication Details

Journal
Birth Defects Research
Published
2025-11-01
DOI
https://doi.org/10.1002/bdr2.2543
Citations
2
Primary Topic
Foot and Ankle Surgery
Type
article
Field-Weighted Citation Impact
3.44
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article

Understanding Clubfoot: Integrating Historical Origins, Embryologic Foundations, Epidemiology and Etiology—A Review

Durai Anand, J S R G Saran, Varun Devdass
2 citations
Birth Defects Research
Foot and Ankle Surgery
3.44
article

Understanding Clubfoot: Integrating Historical Origins, Embryologic Foundations, Epidemiology and Etiology—A Review

Durai Anand, J S R G Saran, Varun Devdass
article en
2 citations

Abstract

CTEV should be considered a systemic developmental dysplasia rather than an isolated foot deformity. The persistence of recurrence and long-term morbidity underscores the need for multidisciplinary research integrating genetics, developmental biology, biomechanics and rehabilitation. Improved understanding of the etiological mechanisms may enable earlier detection, targeted interventions and ultimately better long-term outcomes for affected individuals.

Birth Defects ResearchVol. 117(11)
M S Ramaiah University of Applied Sciences (IN)
Openalex Percentile: Top 7%
Foot and Ankle Surgery
3.44
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Understanding Clubfoot: Integrating Historical Origins, Embryologic Foundations, Epidemiology and Etiology—A Review — Durai Anand, J S R G Saran, et al. · Birth Defects Research (2025) | TGRS Research Map | TGRS