Inflammatory index-based nomogram for risk stratification of erectile dysfunction: a cross-sectional study with dual-cohort validation and mendelian randomization analysis
This study pioneers an inflammation-driven ED nomogram for objective risk stratification, validated across dual cohorts. It also reveals cytokine-specific inflammatory pathways in ED pathogenesis, laying a foundation for personalized ED screening and targeted therapeutic development.
Authors
- Pang Wang (ORCID: https://orcid.org/0009-0006-8770-1708)
- Yixin Zhang (ORCID: https://orcid.org/0000-0003-4632-3780)
- Shanjin Ma (ORCID: https://orcid.org/0000-0002-3370-1466)
- Donghui Han (ORCID: https://orcid.org/0000-0002-3742-4355)
- Zhaokun Shi (ORCID: https://orcid.org/0009-0008-3125-0260)
- Li Guo (ORCID: https://orcid.org/0000-0002-0184-6847)
- Xiangliang Meng
- Wei Hu (ORCID: https://orcid.org/0000-0002-4826-4633)
- Jianhui Bai
- Hong Du (ORCID: https://orcid.org/0000-0002-8470-988X)
- Chao Zhang (ORCID: https://orcid.org/0000-0001-9918-6391)
- Keying Zhang (ORCID: https://orcid.org/0000-0002-7888-7938)
- Yongcai Yu
- Yanan Gu
- Yuli Wu
- Weijun Qin (ORCID: https://orcid.org/0009-0000-4794-3565)
Institutions
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Translational Andrology and Urology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tau-2025-346
- Primary Topic
- Sexual function and dysfunction studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00