Evaluation of Raw Cell-Free DNA Sequences for Gastric Cancer Detection

GastricAI provides a promising noninvasive method for GC detection via cfDNA sequencing, with high sensitivity and reasonable specificity. It holds potential for early screening to improve prognosis, although further prospective studies are needed to validate and refine its clinical utility across diverse populations.

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Publication Details

Journal
JCO Precision Oncology
Published
2025-11-01
DOI
https://doi.org/10.1200/po-25-00204
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

Evaluation of Raw Cell-Free DNA Sequences for Gastric Cancer Detection

Ye Tian, Haixin Li, Jilei Liu, Yubei Huang et al.
JCO Precision Oncology
Cancer Genomics and Diagnostics
article

Evaluation of Raw Cell-Free DNA Sequences for Gastric Cancer Detection

Ye Tian, Haixin Li, Jilei Liu, Yubei Huang, Yuan Pan, Yichen Yang, Zhangyan Lyu, Changyu Sun, Hongru Shen, Fengju Song, Meng Yang, Xiangchun Li, Lei Lei, Wei Wang, Kexin Chen, Yan Guo, Fangfang Song, Yang Li, Na He, Wenqi Wu
article en

Abstract

GastricAI provides a promising noninvasive method for GC detection via cfDNA sequencing, with high sensitivity and reasonable specificity. It holds potential for early screening to improve prognosis, although further prospective studies are needed to validate and refine its clinical utility across diverse populations.

JCO Precision OncologyVol. 9(9)
Tianjin Medical University Cancer Institute and Hospital (CN)
Openalex Percentile: Top 58%
Cancer Genomics and Diagnostics
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