Copper Homeostasis is influenced by Ics3 in Saccharomyces cerevisiae

<i>Saccharomyces cerevisiae</i> has several unique open reading frames that contribute to overall fitness. This study examined <i>ICS3</i> , a contributor of Cu ²⁺ homeostasis. Our results successfully replicate previous work by the Monteiro laboratory using a different method, confirming the positive effect of <i>ICS3</i> on maintaining copper homeostasis for cell growth. No significant difference in growth of <i>ics3Δ</i> mutants was observed for Zn ²⁺ , another oxidative stressor. In addition, <i>MATa</i> and <i>MATα</i> mating types did not influence sensitivity to Cu ²⁺ or Zn ²⁺ .