Incidence and Short‐Term Prognosis of Acute‐On‐Chronic Liver Failure Defined by Japanese Criteria: A Single‐Center Retrospective Cohort Study From Urban Japan
In this Japanese single center cohort, ACLF (per national criteria) was not rare and carried substantial short-term mortality. Age and MELD-Na were dominant prognostic factors, underscoring early trigger control (notably infection, gastrointestinal bleeding, and alcohol cessation) and timely risk stratification in routine care.
Authors
- Shingo Nakamoto
- Hidehiro Kamezaki (ORCID: https://orcid.org/0000-0003-2238-9558)
- Takahiro Maeda (ORCID: https://orcid.org/0000-0003-4530-6460)
- Naoya Kato (ORCID: https://orcid.org/0000-0001-8233-5426)
- Junichi Senoo
- Sadahisa Ogasawara (ORCID: https://orcid.org/0000-0002-6540-9064)
- T. Iwanaga
Institutions
- Chiba University (JP)
- Teikyo University Chiba Medical Center (JP)
Publication Details
- Journal
- JGH Open
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/jgh3.70300
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00