Comparison of immunometabolic profiles in whole blood versus peripheral blood mononuclear cells

These results suggest that WB can be an alternative to PBMCs for metabolic profiling of immune cells. Nevertheless, for some specific cell subsets, caution should be taken when comparing immunometabolic data between WB and PBMCs.

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Publication Details

Journal
Immunometabolism
Published
2025-10-01
DOI
https://doi.org/10.1097/in9.0000000000000073
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00

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Comparison of immunometabolic profiles in whole blood versus peripheral blood mononuclear cells

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Comparison of immunometabolic profiles in whole blood versus peripheral blood mononuclear cells

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article en

Abstract

These results suggest that WB can be an alternative to PBMCs for metabolic profiling of immune cells. Nevertheless, for some specific cell subsets, caution should be taken when comparing immunometabolic data between WB and PBMCs.

ImmunometabolismVol. 7(4)
Leiden University Medical Center (NL), Centre de Recherche Médicales de Lambaréné (GA), Cheikh Anta Diop University (SN)
Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Leids Universitair Medisch Centrum
Openalex Percentile: Top 69%
Single-cell and spatial transcriptomics
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